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Focus

Volume 2, Issue 3

July 2004

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EDITORIAL

July 2004

From the Guest Editor

Alexander Bystritsky, M.D.

Page:331
Published Online:1 July 2004

https://doi.org/10.1176/foc.2.3.331

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CLINICAL SYNTHESIS

July 2004

Diagnosis and Treatment of Anxiety

Alexander Bystritsky, M.D.

Pages:333–342
Published Online:1 July 2004

https://doi.org/10.1176/foc.2.3.333

Abstract
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Anxiety disorders are highly prevalent, disabling conditions. The diagnoses of anxiety disorders are continually undergoing revision. In clinical treatment and research, both dimensional and structural diagnoses can be used, depending on the situation. ...

July 2004

Quick Reference for Anxiety Disorders

Pages:343–345
Published Online:24 January 2015

https://doi.org/10.1176/foc.2.3.343

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REVIEW

July 2004

Generalized Anxiety Disorder

Elizabeth A. Hoge, M.D.,
Julia E. Oppenheimer, B.A., and
Naomi M. Simon, M.D., M.Sc.

Pages:346–359
Published Online:29 January 2015

https://doi.org/10.1176/foc.2.3.346

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July 2004

Patient Management Exercise

Ronald C. Albucher, M.D., and
B. Harrison Levine, M.D., M.P.H.

Pages:360–365
Published Online:1 July 2004

https://doi.org/10.1176/foc.2.3.360

Abstract
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This patient management exercise is designed to test your comprehension of material presented in this issue of Focus as well as your ability to evaluate, diagnose, and manage clinical problems. Answer the questions below, to the best of your ability, on ...

INFLUENTIAL PUBLICATION

July 2004

Pages:366–367
Published Online:1 July 2004

https://doi.org/10.1176/foc.2.3.366

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July 2004

Psychobiological Mechanisms of Resilience and Vulnerability

Dennis S. Charney, M.D.

Pages:368–391
Published Online:1 July 2004

https://doi.org/10.1176/foc.2.3.368

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Objective: Most research on the effects of severe psychological stress has focused on stress-related psychopathology. Here, the author develops psychobiological models of resilience to extreme stress. Method: An integrative model of resilience and ...

July 2004

Cognitive-Behavioral Therapy for Generalized Anxiety Disorder With Integrations From Interpersonal and Experiential Therapies

Thomas D. Borkovec, Ph.D.,
Michelle G. Newman, Ph.D., and
Louis G. Castonguay, Ph.D.

Pages:392–401
Published Online:1 July 2004

https://doi.org/10.1176/foc.2.3.392

Abstract
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After providing background information on the definition and nature of generalized anxiety disorder, this article describes cognitive-behavioral therapy (CBT) methods that have been empirically supported in the treatment of this disorder. Subsequent to ...

July 2004

Neurocircuitry of Anxiety Disorders

Justine M. Kent, M.D., and
Scott L. Rauch, M.D.

Pages:402–409
Published Online:1 July 2004

https://doi.org/10.1176/foc.2.3.402

Abstract
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A major focus in the field of anxiety in the past decade, and an area of intense ongoing interest, is the delineation of the basic neurocircuitry underlying normal and pathologic anxiety. Preclinical work defining the basic neurocircuitry responsible for ...

July 2004

Moving Treatment Research From Clinical Trials to the Real World

Peter P. Roy-Byrne, M.D.,
Cathy D. Sherbourne, Ph.D.,
Michelle G. Craske, Ph.D.,
Murray B. Stein, M.D.,
Wayne Katon, M.D.,
Greer Sullivan, M.D.,
Adrienne Means-Christensen, Ph.D., and
Alexander Bystritsky, M.D.

Pages:410–415
Published Online:1 July 2004

https://doi.org/10.1176/foc.2.3.410

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Recently the National Institutes of Health has been emphasizing research that takes findings generated by clinical research and translates them into treatments for patients who are seen in day-to-day nonresearch settings. This translational process ...

July 2004

Major Depression and Generalised Anxiety Disorder

Kenneth S. Kendler, M.D.

Pages:416–425
Published Online:1 July 2004

https://doi.org/10.1176/foc.2.3.416

Abstract
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In both clinical and epidemiological samples, major depression (MD) and generalised anxiety disorder (GAD) display substantial comorbidity. In a prior analysis of lifetime MD and GAD in female twins, the same genetic factors were shown to influence the ...

July 2004

Neuroanatomical Hypothesis of Panic Disorder, Revised

Jack M. Gorman, M.D.,
Justine M. Kent, M.D.,
Gregory M. Sullivan, M.D., and
Jeremy D. Coplan, M.D.

Pages:426–439
Published Online:1 July 2004

https://doi.org/10.1176/foc.2.3.426

Abstract
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Objective: In a 1989 article, the authors provided a hypothesis for the neuroanatomical basis of panic disorder that attempted to explain why both medication and cognitive behavioral psychotherapy are effective treatments. Here they revise that hypothesis ...

July 2004

Alcohol Dependence and Anxiety Disorders

Marc A. Schuckit, M.D., and
Victor Hesselbrock, Ph.D.

Pages:440–453
Published Online:1 July 2004

https://doi.org/10.1176/foc.2.3.440

Abstract
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Objective: In this critical review the authors evaluate the literature regarding the relationship between lifelong DSM-III-R anxiety disorders and alcohol dependence. Many alcohol-dependent individuals demonstrate severe anxiety symptoms in the context of ...

July 2004

A Review of Pharmacologic Treatments for Obsessive-Compulsive Disorder

Alicia Kaplan, M.D., and
Eric Hollander, M.D.

Pages:454–461
Published Online:1 July 2004

https://doi.org/10.1176/foc.2.3.454

Abstract
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Objective: Obsessive-compulsive disorder is a chronic and often disabling disorder that affects 2 to 3 percent of the U.S. population. Optimal treatment involves a combination of pharmacologic and cognitive-behavioral therapies. Advances in ...

July 2004

Behavioral Versus Pharmacological Treatments of Obsessive Compulsive Disorder

Kenneth A. Kobak,
John H. Greist,
James W. Jefferson,
David J. Katzelnick, and
Henry J. Henk

Pages:462–474
Published Online:1 July 2004

https://doi.org/10.1176/foc.2.3.462

Abstract
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The goal of the study was to provide a quantitative analysis of the relative efficacy of all five currently available serotonin reuptake inhibitors (SRIs) and behavior therapy [exposure and response prevention (ERP)] for obsessive compulsive disorder. The ...

July 2004

Individual, Group, and Multifamily Cognitive-Behavioral Treatments

Barbara L. Van Noppen, M.S.W., and
Gail Steketee, Ph.D.

Pages:475–495
Published Online:1 July 2004

https://doi.org/10.1176/foc.2.3.475

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July 2004

Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections

Susan E. Swedo, M.D.,
Henrietta L. Leonard, M.D.,
Marjorie Garvey, M.D.,
Barbara Mittleman, M.D.,
Albert J. Allen, M.D., Ph.D.,
Susan Perlmutter, M.D.,
Lorraine Lougee, L.C.S.W.,
Sara Dow, B.A.,
Jason Zamkoff, B.A., and
Billinda K. Dubbert, M.S.N.

Pages:496–506
Published Online:1 July 2004

https://doi.org/10.1176/foc.2.3.496

Abstract
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Objective: The purpose of this study was to describe the clinical characteristics of a novel group of patients with obsessive-compulsive disorder (OCD) and tic disorders, designated as pediatric autoimmune neuropsychiatric disorders associated with ...

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