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FOCUS

Volume 14, Issue 4

Clinical Neuropsychiatry

October 2016

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From the Guest Editor

October 2016

Clinical Neuropsychiatry

Margo Lauterbach, M.D.,
Sheldon Benjamin, M.D.

Page:409
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.20160024

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Reviews

October 2016

Mild Traumatic Brain Injury

Thomas W. McAllister, M.D.

Pages:410–421
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.20160025

Abstract
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Mild traumatic brain injury (MTBI) is a significant public health problem worldwide. Injured individuals have an increased relative risk of developing a variety of neuropsychiatric conditions associated with the profile of brain regions typically affected ...

October 2016

Clinical Approaches to Psychogenic Nonepileptic Seizures

Sepideh N Bajestan, M.D., Ph.D., and
W. Curt LaFrance, M.D., M.P.H.

Pages:422–431
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.20160020

Abstract
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Psychogenic nonepileptic seizures (PNES) are a subtype of conversion disorder (also called functional neurological symptom disorder in DSM-5). Patients with PNES are high utilizers of health care and can have disability levels similar to those of patients ...

October 2016

Autoimmune Encephalitis

Michael S. Zandi, Ph.D., M.R.C.P.

Pages:432–436
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.20160019

Abstract
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Antibodies to brain cell-surface proteins have recently been identified in patients whose symptoms cross the boundary between neurology and psychiatry and are associated with syndromes that are responsive to treatment with immunosuppression-based ...

Clinical Synthesis

October 2016

A Clinical Approach to Cognitive Impairment

Vassilis E. Koliatsos, M.D.

Pages:437–447
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.20160026

Abstract
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Cognitive impairment is ubiquitous in medicine and a common experience in everyday life. When severe, persistent, or progressive, it becomes a matter of clinical concern. Top causes of clinically significant cognitive impairment are neurodegenerative ...

October 2016

A Clinical Guide to Frontotemporal Dementias

Peter A. Ljubenkov, M.D., and
Bruce L. Miller, M.D.

Pages:448–464
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.20160018

Abstract
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The term frontotemporal dementia (FTD) describes a diverse group of clinical syndromes, including behavioral-variant FTD (bvFTD), nonfluent/agrammatic-variant primary progressive aphasia (nfvPPA), semantic-variant primary progressive aphasia (svPPA), FTD ...

October 2016

Mood Disorders in Epilepsy

Jay Salpekar, M.D.

Pages:465–472
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.20160017

Abstract
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Mood disorders associated with epilepsy are very common and overrepresented compared with other chronic medical conditions. Depression is a particularly common and worrisome comorbidity, especially because suicidality seems to be increased significantly ...

Ask the Expert

October 2016

Treatment of Aggressive Behavior in Brain Damage

Sheldon Benjamin, M.D.

Pages:473–476
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.20160022

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Ethics Commentary

October 2016

Ethical Considerations in Neuropsychiatric Disorders

Sepideh Bajestan, M.D., Ph.D.,
Juliana Lockman, M.D.,
Laura B. Dunn, M.D.

Pages:477–481
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.20160021

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Communication Commentary

October 2016

Clarify, Condense, Collaborate: Communicating With the Cognitively Challenged Patient

Dorothy E. Stubbe, M.D.

Pages:482–484
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.20160027

First Page
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Patient Management Exercise

October 2016

Is My Son Autistic?

B. Harrison Levine, M.D., M.P.H.

Pages:485–487
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.20160028

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Bibliography

October 2016

Bibliography: Clinical Neuropsychiatry

Pages:488–489
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.140404

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Abstracts

October 2016

Abstracts: Clinical Neuropsychiatry

Pages:490–491
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.140403

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Influential Publications

October 2016

Non-pharmacological Management of Behavioral Symptoms in Frontotemporal and Other Dementias

Cynthia Barton,
Robin Ketelle,
Jennifer Merrilees,
Bruce Miller

Pages:492–498
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.140406

Abstract
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Worldwide prevalence of dementia is predicted to double every 20 years. The most common cause in individuals over 65 is Alzheimer’s disease (AD), but in those under 65, frontotemporal dementia (FTD) is as frequent. The physical and cognitive decline that ...

October 2016

The Neuropsychiatric Spectrum of Motivational Disorders

Jane Epstein, M.D., and
David Silbersweig, M.D.

Pages:499–509
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.140401

Abstract
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Adaptive behavior requires neural systems that mediate the evaluation of stimuli in terms of the well-being of the organism and generate subsequent goal-directed behavior. The authors provide an overview of these systems, with an emphasis on those related ...

October 2016

Anti-NMDA Receptor Encephalitis, Autoimmunity, and Psychosis

Matthew S. Kayser, and
Josep Dalmau

Pages:510–515
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.140405

Abstract
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Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is a recently-discovered synaptic autoimmune disorder in which auto-antibodies target NMDARs in the brain, leading to their removal from the synapse. Patients manifest with prominent psychiatric ...

October 2016

Neuropsychological Correlates of Behavioral Symptoms in Alzheimer’s Disease, Frontal Variant of Frontotemporal, Subcortical Vascular, and Lewy Body Dementias: A Comparative Study

Roberta Perri,
Marco Monaco,
Lucia Fadda,
Carlo Caltagirone, and
Giovanni Augusto Carlesimo

Pages:516–522
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.140407

Abstract
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The aim of this study was to investigate the neuropsychological correlates of behavioral and psychological symptoms (BPSD) in patients affected by various forms of dementia, namely Alzheimer’s disease (AD), frontal-variant frontotemporal dementia (fvFTD), ...

October 2016

Apathy: Why Care?

Robert van Reekum, M.D., F.R.C.P.C.,
Donald T. Stuss, Ph.D.,
Laurie Ostrander, R.N.

Pages:523–532
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.140402

Abstract
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This review presents data showing that apathy is common across a number of disorders. Apathy is not only common, but is also associated with significant problems: reduced functional level, decreased response to treatment, poor illness outcome, caregiver ...

Departments

October 2016

Appreciation to Reviewers

Page:536
Published Online:13 October 2016

https://doi.org/10.1176/appi.focus.140409

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