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Spring 2024 | VOL. 22, NO. 2
Autism Across the Lifespan
CURRENT ISSUE
pp.147-262
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Reproductive Psychiatry: Postpartum Depression is Only the Tip of the Iceberg
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FOCUS

Volume 1, Issue 2

April 2003

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EDITORIAL

April 2003

From the Editor

Kathleen T. Brady, M.D., Ph.D.

Page:113
Published Online:1 April 2003

https://doi.org/10.1176/foc.1.2.113

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CLINICAL SYNTHESIS

April 2003

Evidence-Based Treatments for Substance Use Disorders

Paul B. Gold, Ph.D., and
Kathleen T. Brady, M.D., Ph.D.

Pages:115–122
Published Online:1 April 2003

https://doi.org/10.1176/foc.1.2.115

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A wide variety of evidence-based psychotherapies and pharmacotherapies demonstrate efficacy and effectiveness in the treatment of substance use disorders. Among recent developments in behavioral therapies are expanded uses of contingency management and ...

April 2003

Quick Reference for Substance-Related Disorders

Pages:123–124
Published Online:1 April 2003

https://doi.org/10.1176/foc.1.2.123

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REVIEW

April 2003

Substance-Related Disorders

Avram H. Mack, M.D., and
Richard J. Frances, M.D.

Pages:125–146
Published Online:29 January 2015

https://doi.org/10.1176/foc.1.2.125

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Substance-related disorders are common and cause significant medical, social, and psychological problems among users and those around them. This DSM category comprises a protean set of clinical syndromes, with the different substances exerting various ...

INFLUENTIAL PUBLICATION

April 2003

Bibliography for Substance-Related Disorders

Pages:147–149
Published Online:1 April 2003

https://doi.org/10.1176/foc.1.2.147

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April 2003

Low Level of Brain Dopamine D₂ Receptors in Methamphetamine Abusers: Association With Metabolism in the Orbitofrontal Cortex

Nora D. Volkow, M.D.,
Linda Chang, M.D.,
Gene-Jack Wang, M.D.,
Joanna S. Fowler, Ph.D.,
Yu-Sin Ding, Ph.D.,
Mark Sedler, M.D.,
Jean Logan, Ph.D.,
Dinko Franceschi, M.D.,
John Gatley, Ph.D.,
Robert Hitzemann, Ph.D.,
Andrew Gifford, Ph.D.,
Christopher Wong, M.S., and
Naomi Pappas, M.S.

Pages:150–157
Published Online:1 April 2003

https://doi.org/10.1176/foc.1.2.150

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Objective: The role of dopamine in the addictive process (loss of control and compulsive drug intake) is poorly understood. A consistent finding in drug-addicted subjects is a lower level of dopamine D₂ receptors. In cocaine abusers, low levels of D₂ ...

April 2003

Cannabis Abuse as a Risk Factor for Depressive Symptoms

Gregory B. Bovasso, Ph.D.

Pages:158–162
Published Online:1 April 2003

https://doi.org/10.1176/foc.1.2.158

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Objective: This study sought to estimate the degree to which cannabis abuse is a risk factor for depressive symptoms rather than an effort to self-medicate depression. Method: Participants (N=1,920) in the 1980 Baltimore Epidemiologic Catchment Area (ECA) ...

April 2003

Five-Year Clinical Course Associated With DSM-IV Alcohol Abuse or Dependence in a Large Group of Men and Women

Marc A. Schuckit, M.D.,
Tom L. Smith, Ph.D.,
George P. Danko, Ph.D.,
Kathleen K. Bucholz, Ph.D.,
Theodore Reich, M.D., and
Laura Bierut, M.D.

Pages:163–170
Published Online:1 April 2003

https://doi.org/10.1176/foc.1.2.163

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Objective: The prognostic validity of the DSM-IV diagnoses of alcohol abuse and alcohol dependence was evaluated by examining the 5-year clinical course associated with those diagnoses in a large group of predominantly blue-collar men and women. Method: ...

April 2003

Evidence for a Gender-Related Effect of Alcoholism on Brain Volumes

Daniel W. Hommer, M.D.,
Reza Momenan, Ph.D.,
Erica Kaiser, B.A., and
Robert R. Rawlings, M.S.

Pages:171–178
Published Online:1 April 2003

https://doi.org/10.1176/foc.1.2.171

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Objective: The goal of this study was to compare brain volumes of alcoholic and nonalcoholic men and women and determine if the magnitudes of differences in brain volumes between alcoholic women and nonalcoholic women are greater than the magnitudes of ...

April 2003

Self-Help Treatment for Combined Addiction and Mental Illness

Marc Galanter, M.D.

Pages:179–182
Published Online:1 April 2003

https://doi.org/10.1176/foc.1.2.179

Abstract
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New approaches to treating patients with combined mental illness and substance abuse continue to be developed. This rethinking of treatment is particularly important because of the acknowledged organizational barriers to effective management of persons ...

April 2003

Naltrexone and Cognitive Behavioral Therapy for the Treatment of Outpatient Alcoholics: Results of a Placebo-Controlled Trial

Raymond F. Anton, M.D.,
Darlene H. Moak, M.D.,
L. Randolph Waid, Ph.D.,
Patricia K. Latham, R.N., Ph.D.,
Robert J. Malcolm, M.D., and
James K. Dias, Ph.D.

Pages:183–189
Published Online:1 April 2003

https://doi.org/10.1176/foc.1.2.183

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Objective: The opiate antagonist drug naltrexone has been shown in a few studies with limited sample sizes to be effective when combined with psychosocial therapies for the treatment of alcohol dependence. The goal of this study was to obtain additional ...

April 2003

Addiction Is a Brain Disease, and It Matters

Alan I. Leshner, Ph.D.

Pages:190–193
Published Online:1 April 2003

https://doi.org/10.1176/foc.1.2.190

Abstract
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Scientific advances over the past 20 years have shown that drug addiction is a chronic, relapsing disease that results from the prolonged effects of drugs on the brain. As with many other brain diseases, addiction has embedded behavioral and social-...

April 2003

Science Is Revolutionizing Our View of Addiction—and What to Do About It

Alan I. Leshner, Ph.D.

Pages:194–195
Published Online:1 April 2003

https://doi.org/10.1176/foc.1.2.194

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April 2003

Is ADHD a Risk Factor for Psychoactive Substance Use Disorders? Finding From a Four-Year Prospective Follow-Up Study

Joseph Biederman, M.D.,
Timothy Wilens, M.D.,
Eric Mick, B.A.,
Stephen V. Faraone, Ph.D.,
Wendy Weber, B.A.,
Shannon Curtis, B.A.,
Ayanna Thornell, B.A.,
Kiffany Pfister, B.A.,
Jennifer Garcia Jetton, B.A., and
Jennifer Soriano, B.A.

Pages:196–204
Published Online:1 April 2003

https://doi.org/10.1176/foc.1.2.196

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Objective. To evaluate whether attention-deficit hyperactivity disorder (ADHD) is a risk factor for psychoactive substance use disorders (PSUD), attending to issues of psychiatric comorbidity, family history, and adversity. Method. Using assessments from ...

April 2003

When Does Amphetamine-Induced Psychosis Become Schizophrenia?

Michael Flaum, M.D., and
Susan K. Schultz, M.D.

Pages:205–210
Published Online:1 April 2003

https://doi.org/10.1176/foc.1.2.205

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April 2003

Tests for Drugs of Abuse

Pages:211–212
Published Online:1 April 2003

https://doi.org/10.1176/foc.1.2.211

Abstract
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Testing for drug use has become increasingly common, not only in health care, but also in drug rehabilitation, in the military, at the workplace, after accidents and in the criminal justice system. Performance-enhancing drugs such as anabolic steroids, ...

April 2003

Monitoring the Future: National Results on Adolescent Drug Use: Overview of Key Findings

Lloyd D. Johnston, Ph.D.,
Patrick M. O’Malley, Ph.D., and
Jerald G. Bachman, Ph.D.

Pages:213–234
Published Online:1 April 2003

https://doi.org/10.1176/foc.1.2.213

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