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BibliographyFull Access

Progress in Schizophrenia Research and Treatment

Published Online:https://doi.org/10.1176/appi.focus.18310

This section contains a compilation of recent publications that have shaped the thinking in the field as well as classic works that remain important to the subject reviewed in this issue. This bibliography has been compiled by experts in the field and members of the editorial and advisory boards. Entries are listed chronologically and within topics and years by first author. Articles from the bibliography that are reprinted in this issue are in bold type.

2020

Keepers G, Fochtmann L, Anzia J, et al.: Guideline Writing Group. The American Psychiatric Association Practice Guideline for the Treatment of Patients with Schizophrenia. 2020 American Psychiatric Association. https://www.psychiatry.org/psychiatrists/practice/clinical-practice-guidelinesGoogle Scholar

Taipale H, Lähteenvuo M, Tanskanen A, et al.: Comparative effectiveness of antipsychotics for risk of attempted or completed suicide among persons with schizophrenia. Schizophr Bull, in pressGoogle Scholar

Bowie CR, Bell MD, Fiszdon JM, et al.: Cognitive remediation for schizophrenia: an expert working group white paper on core techniques. Schizophr Res 2020; 215:49–53CrossrefGoogle Scholar

Goldsmith DR, Rapaport MH: Inflammation and negative symptoms of schizophrenia: implications for reward processing and motivational deficits. Front Psychiatry 2020; 11:46CrossrefGoogle Scholar

Ostuzzi G, Papola D, Gastaldon C, et al.: Safety of psychotropic medications in people with COVID-19: evidence review and practical recommendations. BMC Med 2020; 18:215CrossrefGoogle Scholar

Potkin SG, Kane JM, Correll CU, et al.: The neurobiology of treatment-resistant schizophrenia: paths to antipsychotic resistance and a roadmap for future research. NPJ Schizophr 2020; 6:1CrossrefGoogle Scholar

2019

Buchanan A, Sint K, Swanson J, et al.: Correlates of future violence in people being treated for schizophrenia. Am J Psychiatry 2019; 176:694–701CrossrefGoogle Scholar

Cella M, Wykes T: The nuts and bolts of cognitive remediation: exploring how different training components relate to cognitive and functional gains. Schizophr Res 2019; 203:12–16CrossrefGoogle Scholar

Faden J, Citrome L: Resistance is not futile: treatment-refractory schizophrenia—overview, evaluation and treatment. Expert Opin Pharmacother 2019; 20:11–24CrossrefGoogle Scholar

Huhn M, Nikolakopoulou A, Schneider-Thoma J, et al.: Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta-analysis. (published correction appears in Lancet. 2019 Sep 14;394(10202:918) Lancet 2019; 394:939–951CrossrefGoogle Scholar

Iasevoli F, De Luca V, Nucifora FC: Editorial: neurobiology, clinical course, and therapeutic approaches of treatment-resistant schizophrenia: toward an integrated view. Front Psychiatry 2019; 10:870CrossrefGoogle Scholar

Lean M, Fornells-Ambrojo M, Milton A, et al.: Self-management interventions for people with severe mental illness: systematic review and meta-analysis. Br J Psychiatry 2019; 214:260–268CrossrefGoogle Scholar

Marder SR, Cannon TD: Schizophrenia. N Engl J Med 2019; 381:1753–1761CrossrefGoogle Scholar

Roerig JL: Clozapine augmentation strategies. Ment Health Clin 2019; 9:336–348CrossrefGoogle Scholar

Smith RC, Leucht S, Davis JM: Maximizing response to first-line antipsychotics in schizophrenia: a review focused on finding from meta-analysis. Psychopharmacology (Berl) 2019; 236:545–559CrossrefGoogle Scholar

Tiihonen J, Taipale H, Mehtälä J, et al.: Association of antipsychotic polypharmacy vs monotherapy with psychiatric rehospitalization among adults with schizophrenia. JAMA Psychiatry 2019; 76:499–507CrossrefGoogle Scholar

2018

Cassidy RM, Yang F, Kapczinski F, et al.: Risk factors for suicidality in patients with schizophrenia: a systematic review, meta-analysis, and meta-regression of 96 studies. Schizophr Bull 2018; 44:787–797CrossrefGoogle Scholar

Dondé C, Vignaud P, Poulet E, et al.: Management of depression in patients with schizophrenia spectrum disorders: a critical review of international guidelines. Acta Psychiatr Scand 2018; 138:289–299CrossrefGoogle Scholar

Girgis RR, Ciarleglio A, Choo T, et al.: A randomized, double-blind, placebo-controlled clinical trial of tocilizuamb, an interleukin-6 receptor antibody, for residual symptoms in schizophrenia. Neuropsychopharmacology 2018; 43:1317–1323CrossrefGoogle Scholar

Harvey PD, McGurk SR, Mahncke H, et al.: Controversies in computerized cognitive training. Biol Psychiatry Cogn Neurosci Neuroimaging 2018; 3:907–915CrossrefGoogle Scholar

Ijaz S, Bolea B, Davies S, et al.: Antipsychotic polypharmacy and metabolic syndrome in schizophrenia: a review of systematic reviews. BMC Psychiatry 2018; 18:275CrossrefGoogle Scholar

Kesby JP, Eyles DW, McGrath JJ, et al.: Dopamine, psychosis and schizophrenia: the widening gap between basic and clinical neuroscience. Transl Psychiatry 2018; 8:30CrossrefGoogle Scholar

Krynicki CR, Upthegrove R, Deakin JFW, et al.: The relationship between negative symptoms and depression in schizophrenia: a systematic review. Acta Psychiatr Scand 2018; 137:380–390CrossrefGoogle Scholar

Pringsheim T, Gardner D, Addington D, et al.: The assessment and treatment of antipsychotic-induced akathisia. Can J Psychiatry 2018; 63:719–729CrossrefGoogle Scholar

Radua J, Ramella-Cravaro V, Ioannidis JPA, et al.: What causes psychosis? An umbrella review of risk and protective factors. World Psychiatry 2018; 17:49–66CrossrefGoogle Scholar

Taipale H, Mehtälä J, Tanskanen A, et al.: Comparative effectiveness of antipsychotic drugs for rehospitalization in schizophrenia—a nationwide study with 20-year follow-up. Schizophr Bull 2018; 44:1381–1387CrossrefGoogle Scholar

2017

Correll CU, Rubio JM, Inczedy-Farkas G, et al.: Efficacy of 42 pharmacologic cotreatment strategies added to antipsychotic monotherapy in schizophrenia: systematic overview and quality appraisal of the meta-analytic evidence. JAMA Psychiatry 2017; 74:675–684CrossrefGoogle Scholar

Fusar-Poli P, McGorry PD, Kane JM: Improving outcomes of first-episode psychosis: an overview. World Psychiatry 2017; 16:251–265CrossrefGoogle Scholar

Goff DC, Falkai P, Fleischhacker WW, et al.: The long-term effects of antipsychotic medication on clinical course in schizophrenia. Am J Psychiatry 2017; 174:840–849CrossrefGoogle Scholar

Howells FM, Kingdon DG, Baldwin DS: Current and potential pharmacological and psychosocial interventions for anxiety symptoms and disorders in patients with schizophrenia: structured review. Hum Psychopharmacol 2017; 32CrossrefGoogle Scholar

Howes OD, McCutcheon R, Agid O, et al.: Treatment-Resistant Schizophrenia: Treatment Response and Resistance in Psychosis (TRRIP) Working Group Consensus Guidelines on Diagnosis and Terminology. Am J Psychiatry 2017; 174:216–229CrossrefGoogle Scholar

Marder SR, Galderisi S: The current conceptualization of negative symptoms in schizophrenia. World Psychiatry 2017; 16:14–24CrossrefGoogle Scholar

McDonagh MS, Dana T, Selph S, et al.: Treatments for schizophrenia in adults: a systematic review. comparative effectiveness review no. 198. AHRQ pub no. 17(18)-EHC031-EF. Rockville, MD, Agency for Healthcare Research and Quality, Oct 2017. https://effectivehealthcare.ahrq.gov/topics/schizophrenia-adult/research-2017.Google Scholar

Miyaoka T, Wake R, Hashioka S, et al.: Remission of psychosis in treatment-resistant schizophrenia following bone marrow transplantation: a case report. Front Psychiatry 2017; 8:174CrossrefGoogle Scholar

Wimberley T, MacCabe JH, Laursen TM, et al.: Mortality and self-harm in association with clozapine in treatment-resistant schizophrenia. Am J Psychiatry 2017; 174:990–998CrossrefGoogle Scholar

2016

Citrome L, McEvoy JP, Saklad SR: Guide to the management of clozapine-related tolerability and safety concerns. Clin Schizophr Relat Psychoses 2016; 10:163–177CrossrefGoogle Scholar

Dixon LB, Holoshitz Y, Nossel I: Treatment engagement of individuals experiencing mental illness: review and update. World Psychiatry 2016; 15:13–20CrossrefGoogle Scholar

Helfer B, Samara MT, Huhn M, et al.: efficacy and safety of antidepressants added to antipsychotics for schizophrenia: a systematic review and meta-analysis. Am J Psychiatry 2016; 173:876–886CrossrefGoogle Scholar

Miller BJ, Dias JK, Lemos HP, et al.: An open-label, pilot trial of adjunctive tocilizumab in schizophrenia. J Clin Psychiatry 2016; 77:275–276CrossrefGoogle Scholar

Sekar A, Bialas AR, de Rivera H, et al.: Schizophrenia risk from complex variation of complement component 4. Nature 2016; 530:177–183CrossrefGoogle Scholar

Stroup TS, Gerhard T, Crystal S, et al.: Comparative effectiveness of clozapine and standard antipsychotic treatment in adults with schizophrenia. Am J Psychiatry 2016; 173:166–173CrossrefGoogle Scholar

Weiden PJ: Beyond psychopharmacology: emerging psychosocial interventions for core symptoms of schizophrenia. Focus 2016; 14:315–327LinkGoogle Scholar

2015

Czobor P, Van Dorn RA, Citrome L, et al.: Treatment adherence in schizophrenia: a patient-level meta-analysis of combined CATIE and EUFEST studies. Eur Neuropsychopharmacol 2015; 25:1158–1166CrossrefGoogle Scholar

Najjar S, Pearlman DM: Neuroinflammation and white matter pathology in schizophrenia: systematic review. Schizophr Res 2015; 161:102–112CrossrefGoogle Scholar

Petrides G, Malur C, Braga RJ, et al.: Electroconvulsive therapy augmentation in clozapine-resistant schizophrenia: a prospective, randomized study. Am J Psychiatry 2015; 172:52–58CrossrefGoogle Scholar

Sommer IE, van Bekkum DW, Klein H, et al.: Severe chronic psychosis after allogeneic SCT from a schizophrenic sibling. Bone Marrow Transplant 2015; 50:153–154CrossrefGoogle Scholar

Further Reading

Benros ME, Nielsen PR, Nordentoft M, et al.: Autoimmune diseases and severe infections as risk factors for schizophrenia: a 30-year population-based register study. Am J Psychiatry 2011; 168:1303–1310CrossrefGoogle Scholar

Borgwardt SJ, Dickey C, Hulshoff Pol H, et al.: Workshop on defining the significance of progressive brain change in schizophrenia: December 12, 2008 American College of Neuropsychopharmacology (ACNP) All-Day Satellite, Scottsdale, Arizona. The Rapporteurs’ Report. Schizophr Res 2009; 112:32–45CrossrefGoogle Scholar

Brown AS, Derkits EJ: Prenatal infection and schizophrenia: a review of epidemiologic and translational studies. Am J Psychiatry 2010; 167:261–280CrossrefGoogle Scholar

Burns AM, Erickson DH, Brenner CA: Cognitive-behavioral therapy for medication-resistant psychosis: a meta-analytic review. Psychiatr Serv 2014; 65:874–880LinkGoogle Scholar

Cella M, Bishara AJ, Medin E, et al.: Identifying cognitive remediation change through computational modelling--effects on reinforcement learning in schizophrenia. Schizophr Bull 2014; 40:1422–1432CrossrefGoogle Scholar

Correll CU, Rummel-Kluge C, Corves C, et al.: Antipsychotic combinations vs monotherapy in schizophrenia: a meta-analysis of randomized controlled trials. Schizophr Bull 2009; 35:443–457CrossrefGoogle Scholar

Gallego JA, Nielsen J, De Hert M, et al.: Safety and tolerability of antipsychotic polypharmacy. Expert Opin Drug Saf 2012; 11:527–542CrossrefGoogle Scholar

Howes OD, Murray RM: Schizophrenia: an integrated sociodevelopmental–cognitive model. Lancet 2014; 383:1677–1687CrossrefGoogle Scholar

Sommer IE, van Westrhenen R, Begemann MJ, et al.: Efficacy of anti-inflammatory agents to improve symptoms in patients with schizophrenia: an update. Schizophr Bull 2014; 40:181–191CrossrefGoogle Scholar

Turner DT, van der Gaag M, Karyotaki E, et al.: Psychological interventions for psychosis: a meta-analysis of comparative outcome studies. Am J Psychiatry 2014; 171:523–538CrossrefGoogle Scholar

Whitfield-Gabrieli S, Thermenos HW, Milanovic S, et al.: Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia. Proc Natl Acad Sci USA 2009; 106:1279–1284CrossrefGoogle Scholar