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FOCUS

Volume 10, Issue 2

Schizophrenia

April 2012

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From The Guest Editor

April 2012

From the Guest Editors

Peter F. Buckley, M.D., and

Brian J. Miller, M.D., Ph.D., M.P.H.

Pages:113–114
Published Online:1 April 2012

https://doi.org/10.1176/appi.focus.10.2.113

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Clinical Synthesis

April 2012

Is Relapse in Schizophrenia an Immune-Mediated Effect?

Brian J. Miller, M.D., Ph.D., M.P.H., and
Peter F. Buckley, M.D.

Pages:115–123
Published Online:1 April 2012

https://doi.org/10.1176/appi.focus.10.2.115

Abstract
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Clinical course in schizophrenia is often characterized by recurrent relapses, which are associated with adverse outcomes. Immune system abnormalities, including inflammation, have been one of the more enduring findings in the field, and several recent ...

April 2012

Antipsychotic Medication Nonadherence: Risk Factors and Remedies

Oliver Freudenreich, M.D., and
Corinne Cather, Ph.D.

Pages:124–129
Published Online:1 April 2012

https://doi.org/10.1176/appi.focus.10.2.124

Abstract
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Understanding determinants of antipsychotic medication adherence is critical as nonadherence plays a significant role in psychotic relapse and each relapse contributes to accrued social toxicity and disability. “Insight” or lack thereof and a negative ...

April 2012

Managing Medication Effects on Body Weight: Do Behavioral Interventions Work?

Joseph C. Ratliff, Ph.D.,
Erin L. Reutenauer, B.A., and
Cenk Tek, M.D.

Pages:130–139
Published Online:1 April 2012

https://doi.org/10.1176/appi.focus.10.2.130

Abstract
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Individuals with a diagnosis of mental illness have an increased risk for obesity and its related co-morbidities. Several factors contribute to obesity risk in this population: psychotropic medications, psychiatric symptoms, cognitive impairment, and ...

April 2012

Comorbid Alcohol, Cannabis, and Cocaine Use Disorders in Schizophrenia: Epidemiology, Consequences, Mechanisms, and Treatment

Peter H. Addy, Ph.D.,
Rajiv Radhakrishnan, M.D.,
Jose A. Cortes, M.S., and
Deepak Cyril D’Souza, M.D.

Pages:140–153
Published Online:1 April 2012

https://doi.org/10.1176/appi.focus.10.2.140

Abstract
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There are high rates of substance use in patients diagnosed with schizophrenia. The objective of this review is to update clinicians about the epidemiology, consequences, assessment and treatment of comorbid substance use disorders and schizophrenia. ...

April 2012

Ask the Expert: Schizophrenia

Christoph U. Correll, M.D.

Pages:154–156
Published Online:1 April 2012

https://doi.org/10.1176/appi.focus.10.2.154

First Page
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April 2012

Performance in Practice

Farifteh F. Duffy, Ph.D.,
Joyce C. West, Ph.D., M.P.P.,
Laura J. Fochtmann, M.D.,
Lisa Dixon, M.D., M.P.H.,
Julie Kreyenbuhl, Pharm D., Ph.D.,
Eve K. Mościcki, Sc.D., M.P.H.,
Robert Plovnick, M.D., M.S., and
Robert Kunkle, M.A.

Pages:157–171
Published Online:1 April 2012

https://doi.org/10.1176/appi.focus.10.2.157

Abstract
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The Performance in Practice (PIP) Practice Assessment Tool for the Care of Adults with Schizophrenia was developed to help meet the new ABMS and ABPN MOC requirements and to assist psychiatrists in optimizing care to patients. This PIP tool 1) Provides a ...

April 2012

Patient Management Exercise: Experiencing Psychosis

Ian A. Cook, M.D.

Pages:172–176
Published Online:1 April 2012

https://doi.org/10.1176/appi.focus.10.2.172

Abstract
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This exercise is designed to test your comprehension of material presented in this issue of FOCUS as well as your ability to evaluate, diagnose, and manage clinical problems. Answer the questions below, to the best of your ability, on the information ...

April 2012

Communication Commentary: Psychiatric Advance Directives

Dorothy Stubbe, M.D.

Pages:177–179
Published Online:1 April 2012

https://doi.org/10.1176/appi.focus.10.2.177

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April 2012

Ethics Commentary: Ethical Use of Power in High-Risk Situations

Laura Weiss Roberts, M.D., M.A.

Pages:180–185
Published Online:1 April 2012

https://doi.org/10.1176/appi.focus.10.2.180

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Influential Publications

April 2012

Bibliography: Schizophrenia

Pages:186–188
Published Online:1 April 2012

https://doi.org/10.1176/appi.focus.10.2.186

Abstract
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This section contains a compilation of recent publications that have shaped the thinking in the field as well as classic works that remain important to the subject reviewed in this issue. This bibliography has been compiled by experts in the field and ...

April 2012

Abstracts: Schizophrenia

Pages:189–193
Published Online:1 April 2012

https://doi.org/10.1176/appi.focus.10.2.189

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April 2012

The 2009 Schizophrenia PORT Psychopharmacological Treatment Recommendations and Summary Statements

Robert W. Buchanan,
Julie Kreyenbuhl,
Deanna L. Kelly,
Jason M. Noel,
Douglas L. Boggs,
Bernard A. Fischer,
Seth Himelhoch,
Beverly Fang,
Eunice Peterson,
Patrick R. Aquino, and
William Keller

Pages:194–216
Published Online:1 April 2012

https://doi.org/10.1176/appi.focus.10.2.194

Abstract
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In light of the large number of studies published since the 2004 update of Schizophrenia Patient Outcomes Research Team psychopharmacological treatment recommendations, we conducted an extensive literature review to determine whether the current ...

April 2012

Evidence-Based Psychotherapy for Schizophrenia 2011 Update

Faith B. Dickerson, Ph.D., M.P.H., and
Anthony F. Lehman, M.D., M.S.P.H.

Pages:217–225
Published Online:1 April 2012

https://doi.org/10.1176/appi.focus.10.2.217

Abstract
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Many patients with schizophrenia have psychological distress and receive some form of psychotherapy. Several different psychotherapeutic approaches for schizophrenia have been developed and studied. Of these approaches, cognitive behavior therapy (CBT) ...

April 2012

The NIMH-CATIE Schizophrenia Study: What Did We Learn?

Jeffrey A. Lieberman, M.D., and
T. Scott Stroup, M.D., M.P.H.

Pages:226–230
Published Online:1 April 2012

https://doi.org/10.1176/appi.focus.10.2.226

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April 2012

Risperidone Nonadherence and Return of Positive Symptoms in the Early Course of Schizophrenia

Kenneth L. Subotnik, Ph.D.,
Keith H. Nuechterlein, Ph.D.,
Joseph Ventura, Ph.D.,
Michael J. Gitlin, M.D.,
Stephen Marder, M.D.,
Jim Mintz, Ph.D.,
Gerhard S. Hellemann, Ph.D.,
Leslie A. Thornton, Ph.D., and
Indira R. Singh, B.S.

Pages:231–238
Published Online:1 April 2012

https://doi.org/10.1176/appi.focus.10.2.231

Abstract
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Objective: This study examined the effect of medication nonadherence on the return of positive symptoms among recent-onset schizophrenia patients. Method: Three sets of operational criteria for medication nonadherence with differing levels of severity ...

April 2012

Perspectives on Systems of Care

Marvin S. Swartz, M.D.

Page:239
Published Online:1 April 2012

https://doi.org/10.1176/appi.focus.10.2.239

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April 2012

Medicaid Cutbacks and State Psychiatric Hospitalization of Patients With Schizophrenia

Bentson H. McFarland, M.D., Ph.D., and
Jon C. Collins, Ph.D.

Pages:240–248
Published Online:1 April 2012

https://doi.org/10.1176/appi.focus.10.2.240

Abstract
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Objective: Given financial difficulties precipitated by the flagging national economy, state policy makers are interested in the impact of Medicaid cutbacks on individuals with schizophrenia. Starting in 2003, the Oregon legislature eliminated all ...

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