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Patient Management ExerciseFull Access

Treating Posttraumatic Stress Disorder in Primary Care

This exercise is designed to test your comprehension of material relevant to this issue of Focus as well as your ability to evaluate, diagnose, and manage clinical problems. Answer the questions below to the best of your ability with the information provided, making your decisions as if the individual were one of your patients.

Questions are presented at “consideration points” that follow a section that gives information about the case. One or more choices may be correct for each question; make your choices on the basis of your clinical knowledge and the history provided. Read all of the options for each question before making any selections. You are given points on a graded scale for the best possible answer(s), and points are deducted for answers that would result in a poor outcome or delay your arriving at the right answer. Answers that have little or no impact receive zero points. At the end of the exercise, you will add up your points to obtain a total score.

Case Vignette

You are the embedded psychiatrist working at a Family Health Center. Dr. Matthews, a primary care physician, refers Mrs. R to you for psychiatric consultation. Mrs. R is a 32-year-old woman whom Dr. Matthews recently began following for dizziness and migraine headaches. He suspects there is a component of anxiety to his patient’s presentation and would like treatment recommendations.

During your interview with her, Mrs. R reports worsening mood for the past month. She describes feeling “on edge” and needing to watch her surroundings. In the past year she had felt similar symptoms, but they seemed to be controlled until recently. She denies persistent depressed mood, suicidal ideations, or changes in appetite, hopelessness, or helplessness. She states that about a month and a half ago she ran into a man who had sexually abused her five years previously. Since running into him again, she notices increased frequency of episodes of reliving the assault (about three times per week), daily nightmares with nighttime awakening, and not feeling rested. She wakes up sweating and very distressed, and she experiences palpitations and extreme fear. She has been staying home more than usual because she fears running into this man again. Her family members are concerned that she has cancelled plans with them several times in the past few weeks and seems distant. She denies auditory or visual hallucinations. She denies symptoms of paranoia but describes a general sense of being unsafe. She complains of having “dizzy spells” during the day and frequent headaches. Mrs. R is not receiving any type of psychiatric treatment. She takes only multivitamins and ibuprofen for headaches as needed.

Consideration Point A

At this point, what is the most likely diagnosis?

A1.

Major depressive disorder, recurrent

A2.

Adjustment disorder with depressed mood

A3.

Panic disorder

A4.

Posttraumatic stress disorder (PTSD)

A5.

Conversion disorder

Case Vignette Continues

Mrs. R reports that she grew up in an unstable home environment. She witnessed domestic violence between her parents until age 12, when they separated and she moved to a shelter for victims of abuse. She denies being physically abused by her father but has clear memories of the injuries her mother suffered. As a child she had trouble in school. She remembers going to the nurse’s office often because of abdominal pain or headaches and being sent home. She had difficulty focusing on the lessons and endorsed frequent fear for her mother’s well-being. Her mother was diagnosed as having major depressive disorder and PTSD. Mrs. R believes her father was an alcoholic, but she is unsure of other family psychiatric history. Mrs. R denies past suicide attempts but admits to having thoughts that life is not worth living since early in her life.

Consideration Point B

Which screening measure would have been most helpful if the primary care physician had used it during Mrs. R’s visit?

B1.

Patient Health Questionnaire–9 (PHQ-9)

B2.

Seven-Item Generalized Anxiety Disorder scale (GAD-7)

B3.

Primary Care PTSD Screen (PC-PTSD)

B4.

Screen for Child Anxiety Related Disorders (SCARED)

B5.

CRAFFT Screening Test

Consideration Point C

What recommendations would you provide for Dr. Matthews?

C1.

Support the patient and monitor for worsening symptoms.

C2.

Admit to the psychiatric hospital.

C3.

Refer for psychotherapy and consider starting prazosin for nightmares.

C4.

Begin quetiapine 50 mg p.o. q.h.s.

C5.

Begin trial of fluoxetine for at least 12 weeks.

Answers: Scoring, Relative Weights, and Comments

Consideration Point A

A1.

(–1) Major depressive disorder, recurrent. Mrs. R denies having depressed mood and is not anhedonic. Presence of depression or anhedonia in addition to other supporting symptoms would meet the criteria for major depressive disorder.

A2.

(−2) Adjustment disorder with depressed mood. An adjustment disorder with depressed mood includes symptoms such as low mood, tearfulness, or a feeling of hopelessness within six months of an acute stressor. This does not apply to Mrs. R, because she denies experiencing low mood and hopelessness, and her symptoms are an acute exacerbation of chronic symptomatology.

A3.

(−1) Panic disorder. While Mrs. R has panic-like symptoms, the accumulation of all her symptoms and signs is most consistent with PTSD. She is having nightmares and reliving the sexual assault episode frequently. She wakes up at night feeling scared. She also suffers from dizziness and headaches and feels unsafe.

A4.

(+3) PTSD. Criteria for PTSD include exposure to or direct experience of trauma or witnessing a traumatic event. In this case, the patient was sexually abused five years ago and had witnessed domestic violence between her parents in childhood. She grew up fearing for her mother’s safety and well-being. She reports experiencing flashbacks and reliving the assault episode and is fearful about her safety.

A5.

(−2) Conversion disorder. Conversion disorder is a condition in which psychological stress is expressed with physical symptoms leading to functional impairment. It affects a patient’s ability to walk, swallow, see, or hear. Mrs. R does not report any altered voluntary motor or sensory function that corresponds with conversion disorder.

Consideration Point B

B1.

(−1) PHQ-9. This is a multipurpose instrument for screening, diagnosing, monitoring, and measuring the severity of depression. It may not be useful in this case, because the patient does not endorse symptoms of depressive disorder.

B2.

(−1) GAD-7. The GAD-7 focuses on generalized anxiety disorder (GAD), whereas Mrs. R’s symptoms are more suggestive of PTSD.

B3.

(+3) PC-PTSD. The PC-PTSD is a self-reporting tool for PTSD that comprises four items that correspond to PTSD symptoms. This instrument would work well as a screening test with this patient, because she exhibits multiple PTSD symptoms. Patients who score positive on the PC-PTSD should be evaluated further.

B4.

(−2) SCARED. This child and parent self-report scale is used to assess childhood anxiety disorders, including GAD, separation anxiety disorder, panic disorder, and social phobia. The target population includes children between the ages of eight and 18 years. It does not apply in this case because the patient is an adult.

B5.

(−2) CRAFFT. This screening test is used to screen adolescents for substance use disorders and includes questions that are designed to be appropriate for teenagers. This screening tool is not relevant for the case described here because the patient is an adult and substance use disorder is not evident.

Consideration Point C

C1.

(+1) Support the patient and monitor for worsening symptoms. This option should be considered in addition to recommended treatment. The patient should be educated about the effects of trauma and the fact that there are treatments for PTSD.

C2.

(−2) Admit to the psychiatric hospital. The severity of the symptoms does not indicate the need to admit the patient to the psychiatric hospital at this point.

C3.

(+3) Refer for psychotherapy. Studies have shown that cognitive-behavioral therapy (CBT) is effective in relieving PTSD symptoms. Specific types of cognitive-behavioral treatment include cognition therapy, stress inoculation therapy, and exposure therapy. These therapies have been equally effective when used individually and in combination. You should also strongly endorse the patient’s compliance with treatment and regular follow-up visits.

C4.

(−2) Begin quetiapine 50 mg p.o. q.h.s. Although antipsychotics are sometimes prescribed to treat PTSD related to mood and anxiety symptoms, at this time option 3 listed above is the best course for the patient.

C5.

(+2) Begin trial of fluoxetine for at least 12 weeks. Selective serotonin reuptake inhibitors (SSRIs) are considered the first-line pharmacological treatment for PTSD in civilian populations. This option should be considered along with referral for psychotherapy and other additional interventions.

Conclusion

It is estimated that PTSD prevails in 7% to 8% of the general population; about 10% of women and 5% of men develop this disorder at some point in their lives. Because patients often go to primary care providers to seek medical care for the issues associated with PTSD, this rate is two to three times higher in primary care settings. Data suggest that approximately 30% of women will be sexually abused at some point in their lifetimes. As a result, 25% to 50% of those women will develop PTSD. For men, violence, especially combat-related violence, is the leading cause of the disorder (1).

Because patients approach primary care providers first to receive health care, primary care providers play a central role in mental illness management in the United States. Primary care providers treat 40%−60% of patients with mental disorders and prescribe 80% of antidepressant medications and around 60% of all psychotropic drugs (2). However, many primary care settings are ill-prepared to manage the mental health needs of patients because of a lack of resources. The collaborative care model has been successful in addressing this issue by shifting the focus from intervening at the individual level to restructuring the primary care delivery system to integrate a set of coordinated components.

It is often observed that patients with general medical complaints have been exposed to traumatic events and have PTSD symptoms but have not received appropriate diagnosis and mental health care. In primary care settings, these patients are not often recognized and do not receive necessary counseling and referral to a mental health provider. Because PTSD patients tend to avoid trauma reminders, it is very unlikely that they will report their traumatic experiences and related symptoms spontaneously. Therefore, primary care providers need to look for signs and symptoms of PTSD, which can be further validated by using appropriate screening tools. There are several PTSD screening tools available; however, the PC-PTSD is considered one of the most useful instruments for primary care providers. This four-item tool helps address unique PTSD symptoms such as reexperiencing, avoidance/numbing, and hyperarousal.

PTSD is generally treated with a combination of psychotherapy and pharmacotherapy. Popular psychotherapy approaches include trauma-focused CBT, stress inoculation training, cognitive processing therapy, eye movement desensitization and reprocessing therapy, and exposure therapy. SSRIs are the first-line pharmacological therapy used to manage chronic and acute PTSD. Second-line therapeutic options such as other classes of antidepressants, benzodiazepines and nonbenzodiazepine hypnotics, second-generation antipsychotics, and mood-stabilizing agents are also used in addition to cognitive therapy and SSRIs to target specific symptoms of PTSD.

Your Total

Your Total

Enlarge table
Dr. Padilla is senior associate training director of the Psychiatry Residency Training Program, Department of Psychiatry, University of Massachusetts Medical School, Worcester. Ms. Patel and Dr. Parekh are with the Division of Diversity and Health Equity, American Psychiatric Association, Arlington, Virginia.
Send correspondence to Dr. Padilla (e-mail: ).

The authors report no financial relationships with commercial interests.

References

1 Freedy JR, Brock CD: Spotting-and treating-PTSD in primary care. J Fam Pract 2010; 59:75–80Google Scholar

2 Belsher BE, Curry J, McCutchan P, et al.: Implementation of a collaborative care initiative for PTSD and depression in the army primary care system. Soc Work Ment Health 2014; 12:500–522CrossrefGoogle Scholar