Suicide is the tragic outcome of a diverse interplay of biological, psychological, and social factors. Suicide affects all people and has long been considered a complex, but preventable, cause of disease burden throughout the world. Despite improvements in awareness and treatment, suicide continues to account for 1 million deaths annually—one life lost every 40 seconds. Suicide occurs in the general population at a rate of 11.3/100,000 in the United States. Suicide attempts occur even more frequently. For every death by suicide, the Institute of Medicine (IOM) reports that an additional 25 nonfatal suicide attempts (100-200 for youth) are estimated to occur. Suicide attempts are associated with approximately 500,000 emergency room visits every year in the United States alone (1). Risk for suicide cuts across mental disorders, socioeconomic status, age, and gender, and “psychological autopsy” studies indicate that nearly all suicide decedents have at least one psychiatric disorder at the time of death (2).